**Keywords**:
computer-science
or
Inferential statistics

This course distills for you expert knowledge and skills mastered by professionals in Health Big Data Science and Bioinformatics. You will learn exciting facts about the human body biology and chemistry, genetics, and medicine that will be intertwined with the science of Big Data and skills to...

In this course, you will learn how to use the BaseSpace cloud platform developed by Illumina (our industry partner) to apply several standard bioinformatics software approaches to real biological data. In particular, in a series of Application Challenges will see how genome assembly can be used...

Named a top 50 MOOC of all time by Class Central! This course begins a series of classes illustrating the power of computing in modern biology. Please join us on the frontier of bioinformatics to look for hidden messages in DNA without ever needing to put on a lab coat. In the first half of the...

In previous courses in the Specialization, we have discussed how to sequence and compare genomes. This course will cover advanced topics in finding mutations lurking within DNA and proteins. In the first half of the course, we would like to ask how an individual's genome differs from the...

You may have heard a lot about genome sequencing and its potential to usher in an era of personalized medicine, but what does it mean to sequence a genome? Biologists still cannot read the nucleotides of an entire genome as you would read a book from beginning to end. However, they can read...

Are you interested in learning how to program (in Python) within a scientific setting? This course will cover algorithms for solving various biological problems along with a handful of programming challenges helping you implement these algorithms in Python. It offers a gently-paced introduction...

How do we infer which genes orchestrate various processes in the cell? How did humans migrate out of Africa and spread around the world? In this class, we will see that these two seemingly different questions can be addressed using similar algorithmic and machine learning techniques arising from...

Once we have sequenced genomes in the previous course, we would like to compare them to determine how species have evolved and what makes them different. In the first half of the course, we will compare two short biological sequences, such as genes (i.e., short sequences of DNA) or proteins. We...

In the previous course in the Specialization, we learned how to compare genes, proteins, and genomes. One way we can use these methods is in order to construct a "Tree of Life" showing how a large collection of related organisms have evolved over time. In the first half of the course, we will...

You already know a good bit about hypothesis testing with one or two samples. Now we take things further by making inferences based on three or more samples. We'll use the very special F-distribution to do it (F stands for "fabulous").

You've gotten good at hypothesis testing when you can make assumptions about the underlying distributions. In this tutorial, we'll learn about a new distribution (the chi-square one) and how it can help you (yes, you) infer what an underlying distribution even is!

You're already familiar with hypothesis testing with one sample. In this tutorial, we'll go further by testing whether the difference between the means of two samples seems to be unlikely purely due to chance.

This tutorial helps us answer one of the most important questions not only in statistics, but all of science: how confident are we that a result from a new drug or process is not due to random chance but due to an actual impact. If you are familiar with sampling distributions and confidence...

Ever wondered what pollsters are talking about when they said that there is a 3% "margin of error" in their results. Well, this tutorial will not only explain what it means, but give you the tools and understanding to be a pollster yourself!

We all have confidence intervals ("I'm the king of the world!!!!") and non-confidence intervals ("No one loves me"). That is not what this tutorial is about. This tutorial takes what you already know about the central limit theorem, sampling distributions, and z-scores and uses these tools to...

In this tutorial, we experience one of the most exciting ideas in statistics--the central limit theorem. Without it, it would be a lot harder to make any inferences about population parameters given sample statistics. It tells us that, regardless of what the population distribution looks like,...

The normal distribution (often referred to as the "bell curve" is at the core of most of inferential statistics. By assuming that most complex processes result in a normal distribution (we'll see why this is reasonable), we can gauge the probability of it happening by chance. To best enjoy this...