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Target audience: post-docs 

Using bioinformatics to hunt SARS-CoV-2, its variants & its origins – a practical guide

This Practical Guide outlines basic bioinformatics approaches for exploring the SARS-CoV-2 genome and its corresponding proteins, focusing on the protein exposed on the viral particle surface: the spike protein. The ways in which bioinformatics can be harnessed to study a new virus, its genome,...

Keywords: Bioinformatics for schools, basic bioinformatics, SARS-CoV-2 pandemic, genome analysis, protein sequence analysis, protein structure analysis, virus variants, spike protein, training material

Resource type: Training materials

Using bioinformatics to hunt SARS-CoV-2, its variants & its origins – a practical guide http://tess.elixir-uk.org/materials/using-bioinformatics-to-hunt-sars-cov-2-its-variants-its-origins-a-practical-guide This Practical Guide outlines basic bioinformatics approaches for exploring the SARS-CoV-2 genome and its corresponding proteins, focusing on the protein exposed on the viral particle surface: the spike protein. The ways in which bioinformatics can be harnessed to study a new virus, its genome, its proteins, its origins and its evolution are explored. Bioinformatics for schools, basic bioinformatics, SARS-CoV-2 pandemic, genome analysis, protein sequence analysis, protein structure analysis, virus variants, spike protein, training material Trainers Training instructors Training Designers PhD students post-docs Life Science Researchers
Adding ontology terms

This tutorial describes how terms can be added to the eNanoMapper ontology.

Keywords: enanomapper, ontologies

Resource type: Tutorial

Adding ontology terms http://tess.elixir-uk.org/materials/adding-ontology-terms-2d31ae63-7f7b-45df-aa37-4b1e14209183 This tutorial describes how terms can be added to the eNanoMapper ontology. enanomapper, ontologies post-docs
RRegrs package

This tutorial explains how to use a collection of R regression tools for estimating the optimal model via a fully validated procedure.

Keywords: Regression Models

RRegrs package http://tess.elixir-uk.org/materials/rregrs-package This tutorial explains how to use a collection of R regression tools for estimating the optimal model via a fully validated procedure. Regression Models PhD students post-docs
How to use the AffyQC web tool of ArrayAnalysis.org for quality control and pre-processing of Affymetrix microarray data

This tutorial explains how to use the AffyQC web tool of ArrayAnalysis.org for quality control and pre-processing of Affymetrix microarray data.

Keywords: Microarray data analysis, Quality control and data pre-processing, Affymetrix microarrays, Systems biology, Pathway and network analyis

How to use the AffyQC web tool of ArrayAnalysis.org for quality control and pre-processing of Affymetrix microarray data http://tess.elixir-uk.org/materials/how-to-use-the-affyqc-web-tool-of-arrayanalysis-org-for-quality-control-and-pre-processing-of-affymetrix-microarray-data This tutorial explains how to use the AffyQC web tool of ArrayAnalysis.org for quality control and pre-processing of Affymetrix microarray data. Microarray data analysis, Quality control and data pre-processing, Affymetrix microarrays, Systems biology, Pathway and network analyis PhD students post-docs
How to use the statistics module of ArrayAnalysis.org for statistics analysis of microarray data

This tutorial how to statistically analyze microarray data with ArrayAnalysis.org website.

Keywords: ArrayAnalysis.org, microarray

How to use the statistics module of ArrayAnalysis.org for statistics analysis of microarray data http://tess.elixir-uk.org/materials/how-to-use-the-statistics-module-of-arrayanalysis-org-for-statistics-analysis-of-microarray-data This tutorial how to statistically analyze microarray data with ArrayAnalysis.org website. ArrayAnalysis.org, microarray post-docs
How to make a new pathway for WikiPathways using PathVisio

This tutorial explains how to a new pathway for WikiPathways using PathVisio.

Keywords: Systems biology, Pathway analysis, Network analysis, Microarray data analysis, Nanomaterials

How to make a new pathway for WikiPathways using PathVisio http://tess.elixir-uk.org/materials/how-to-make-a-new-pathway-for-wikipathways-using-pathvisio This tutorial explains how to a new pathway for WikiPathways using PathVisio. Systems biology, Pathway analysis, Network analysis, Microarray data analysis, Nanomaterials PhD students post-docs
Omics descriptors calculation R package

This tutorial explains how to generate a new set of GO descriptors using two novel created R packages.

Keywords: Gene Ontology

Omics descriptors calculation R package http://tess.elixir-uk.org/materials/omics-descriptors-calculation-r-package This tutorial explains how to generate a new set of GO descriptors using two novel created R packages. Gene Ontology PhD students post-docs
Pathway module of ArrayAnalysis.org

This tutorial explains how to use the Pathway module of ArrayAnalysis.org for pathway analysis of microarray data.

Keywords: Gene Ontology

Pathway module of ArrayAnalysis.org http://tess.elixir-uk.org/materials/pathway-module-of-arrayanalysis-org This tutorial explains how to use the Pathway module of ArrayAnalysis.org for pathway analysis of microarray data. Gene Ontology PhD students post-docs
Entering and analysing nano safety data

Tutorial that covers various aspects of working with the eNanoMapper database. It discussed searching, adding, and downloading data from an eNanoMapper database.

Keywords: ontologies, enanomapper

Entering and analysing nano safety data http://tess.elixir-uk.org/materials/entering-and-analysing-nano-safety-data Tutorial that covers various aspects of working with the eNanoMapper database. It discussed searching, adding, and downloading data from an eNanoMapper database. ontologies, enanomapper Bioinformatician PhD students post-docs
Adding ontology terms

This tutorial describes how terms can be added to the eNanoMapper ontology.

Keywords: enanomapper, ontologies

Adding ontology terms http://tess.elixir-uk.org/materials/adding-ontology-terms This tutorial describes how terms can be added to the eNanoMapper ontology. enanomapper, ontologies post-docs
Browsing the eNanoMapper ontology with BioPortal, AberOWL and Protégé

This tutorial explains how the eNanoMapper ontology can be browsed with three tools, of which two are online.

Keywords: nanotoxicology, Ontologies, BioPortal, AberOWL, Protégé

Resource type: Tutorial

Browsing the eNanoMapper ontology with BioPortal, AberOWL and Protégé http://tess.elixir-uk.org/materials/browsing-the-enanomapper-ontology-with-bioportal-aberowl-and-protege This tutorial explains how the eNanoMapper ontology can be browsed with three tools, of which two are online. nanotoxicology, Ontologies, BioPortal, AberOWL, Protégé PhD students post-docs
Probabilistic programming with (R)Stan

Probabilistic models describe how the observed data was generated, and what structure the signal and noise from potentially multiple sources may have. Many classical statistical models are special cases of probabilistic models with special modeling assumptions. Probabilistic models can be...

Scientific topics: Statistics and probability

Probabilistic programming with (R)Stan http://tess.elixir-uk.org/materials/probabilistic-programming-with-r-stan Probabilistic models describe how the observed data was generated, and what structure the signal and noise from potentially multiple sources may have. Many classical statistical models are special cases of probabilistic models with special modeling assumptions. Probabilistic models can be implemented, improved, and critizised in a flexible, explicit and transparent manner, and the analysis can be supported with prior information about the data. This 1-day course provides an introduction to Bayesian/probabilistic models. We will implement standard linear models based on the rstanarm package of the R statistical programming environment and readily available example data sets. The workshop is an ideal opportunity to familiarize yourself with the basic ideas in probabilistic modeling such as prior information, likelihood, model criticism and validation, as well as some of the available tools. At the end, you should be able to implement basic probabilistic models yourself, and understand their relative advantages and pitfalls compared to their classical alternatives. Statistics and probability Life Science Researchers PhD students beginner bioinformaticians post-docs 2016-04-22
Image Ethics and Poster Design

The image ethics part handles on the theoretical aspects of image manipulation, the mistakes people make and how to avoid image fraud. VIB has guidelines for acceptable scientific image manipulations. Not all manipulations are scientifically correct. There are manipulations that fall within the...

Scientific topics: Image

Image Ethics and Poster Design http://tess.elixir-uk.org/materials/image-ethics-and-poster-design The image ethics part handles on the theoretical aspects of image manipulation, the mistakes people make and how to avoid image fraud. VIB has guidelines for acceptable scientific image manipulations. Not all manipulations are scientifically correct. There are manipulations that fall within the scope of scientific misconduct, because they result in misrepresentation of the data. Such misrepresentation makes it impossible for others to interpret the data correctly, or worse, leads to conclusions that are not correct. The second part of this course deals with poster design. Scientific posters are a resume of a piece or timespan of research on one square meter of paper. They are best compared to slides for oral presentations, not a written document. Posters can’t convey detailed evidence like scientific articles, it must visualize a message on its own. When standing a meter away from a poster you hardly feel like reading much text, especially when the author/designer stands next to it. A poster must bring that message without requiring oral explanation, but with as little text as possible. Prerequisites Participants must have experience with GIMP and Inkscape. Schedule See the TRAINING AT VIB website for a detailed schedule of this training. Training material Not available Links Not available Scientific topics Image data Target audience Life Science Researchers, PhD students, post-docs, beginner bioinformaticians   Image Life Science Researchers PhD students beginner bioinformaticians post-docs 2016-04-22
Analysis of metabolome data

This training will focus on the processing of raw data obtained via either Gas Chromatography- (GC) or Liquid Chromatography- (LC) mass spectrometry (MS). In addition, based on the comparative analysis between two sample sets (e.g. control vs treatment), the subsequent identification of...

Scientific topics: Metabolomics

Analysis of metabolome data http://tess.elixir-uk.org/materials/analysis-of-metabolome-data This training will focus on the processing of raw data obtained via either Gas Chromatography- (GC) or Liquid Chromatography- (LC) mass spectrometry (MS). In addition, based on the comparative analysis between two sample sets (e.g. control vs treatment), the subsequent identification of differential metabolites will be introduced. Afterwards, the trainee should be able to perform independently a comparative analysis of raw metabolome data and to pinpoint the well-known metabolites in the chromatogram. Metabolomics Life Science Researchers PhD students beginner bioinformaticians post-docs 2016-04-22
Advanced FlowJo training

The training will start with an introduction to FlowJo v10 but there will be enough details and features to make it worth even for advanced users. In the afternoon, advanced tools in FlowJo and new plugins (tSNE, SPADE) will be presented showing you how to work in high...

Advanced FlowJo training http://tess.elixir-uk.org/materials/advanced-flowjo-training The training will start with an introduction to FlowJo v10 but there will be enough details and features to make it worth even for advanced users. In the afternoon, advanced tools in FlowJo and new plugins (tSNE, SPADE) will be presented showing you how to work in high dimensionality. Prerequisites Participants must have experience with FlowJo. Schedule See the TRAINING AT VIB website for a detailed schedule of this training. Training material Not available Links Not available Scientific topics FlowJo Target audience Life Science Researchers, PhD students, post-docs, beginner bioinformaticians Life Science Researchers PhD students beginner bioinformaticians post-docs 2016-04-22
A tour of machine learning - classification

Machine learning has become ubiquitous in biotechnology (as in many other fields), fueled largely by the increasing availability and amount of data. Learning algorithms can figure out how to perform important tasks by generalizing examples. Typical applications are diagnoses/prognoses,...

Scientific topics: Machine learning

A tour of machine learning - classification http://tess.elixir-uk.org/materials/a-tour-of-machine-learning-classification Machine learning has become ubiquitous in biotechnology (as in many other fields), fueled largely by the increasing availability and amount of data. Learning algorithms can figure out how to perform important tasks by generalizing examples. Typical applications are diagnoses/prognoses, gene/protein annotation, drug design, image recognition, text mining and many others. However, building successful machine learning models requires a substantial amount of “black art” that is hard to find in textbooks. This course is an interactive Jupyter Notebook (Python) that will teach you how to build successful machine learning models. No background in machine learning is assumed, just a keen interest. Machine learning Life Science Researchers PhD students beginner bioinformaticians post-docs 2016-04-22
Introduction to Biopython

Biopython is the best-known Python library to process biological data. This training is aimed to empower you to use Biopython to make your research more efficient. The first day of the training is to give an overview of Biopython. You are going to start with your first steps in Biopython on the...

Scientific topics: Software engineering

Introduction to Biopython http://tess.elixir-uk.org/materials/introduction-to-biopython-8ccf2441-bd7d-46f2-84f8-c2b123844a23 Biopython is the best-known Python library to process biological data. This training is aimed to empower you to use Biopython to make your research more efficient. The first day of the training is to give an overview of Biopython. You are going to start with your first steps in Biopython on the command line. Afterwards you will take a tour of the most important components: sequences, NCBI queries, BLAST, trees, and 3D structures. You will try each of these modules on practical examples. Please don't hesitate to ask questions about Python basics or particular data formats (e.g. XML or NGS data). The second day of the training is to broaden your perspective: What other features does the library have? How can you use the documentation effectively? What is Biopython not capable of? What can I do to visualize my data? Are there alternatives? If you have your own data that you would like to work on with Biopython in more detail, there is room for that. For us, the most important thing is to identify concrete Python modules and functions that help you to get your research done. Participants are encouraged to submit a description of their research topic and/or the questions they would like to answer with Biopython. Additionally, participants can bring their own data that they would like to process in Python to the training. Software engineering Life Science Researchers PhD students beginner bioinformaticians post-docs 2016-04-22 2017-10-09
Signalling Networks: From Data to Modelling

What is the course about? Signalling pathways and networks are very important to regulate and control cellular processes, cell fate, and their malfunctions often lead to diseases, such as cancer or diabetes. This course provides an introductory overview of the most useful resources and tools to...

Keywords: Signalling

Signalling Networks: From Data to Modelling http://tess.elixir-uk.org/materials/signalling-networks-from-data-to-modelling What is the course about? Signalling pathways and networks are very important to regulate and control cellular processes, cell fate, and their malfunctions often lead to diseases, such as cancer or diabetes. This course provides an introductory overview of the most useful resources and tools to investigate signalling pathways and networks, and also introduces basic approaches to model signalling events. The hands-on training will give a wide overview of tools and concepts related to signalling networks. What will I Learn? In this course you will learn how to use Cytoscape, where to find the most reliable signaling data, how to reconstruct, analyze and visualize a network. You will also learn how to develop your own models, mostly with logic modelling, what other modelling approaches exist, and how you can apply a model for your own research work. Signalling Grad students post-docs 2016-04-14 2017-10-09
Electronic Lab Notebook Introduction - Ghent

The Training consists of two parts: Introduction Access ways to your notebook, ELN installation instructions and house rules, where to find documentation and get support Hands-on-demo Creating notebooks/experiments, importing and exporting (MS Office) files, sharing data, using templates,...

Electronic Lab Notebook Introduction - Ghent http://tess.elixir-uk.org/materials/electronic-lab-notebook-introduction The Training consists of two parts: Introduction Access ways to your notebook, ELN installation instructions and house rules, where to find documentation and get support Hands-on-demo Creating notebooks/experiments, importing and exporting (MS Office) files, sharing data, using templates, advanced searching, printing, tips and tricks Life Science Researchers PhD students post-docs 2016-04-22 2017-10-09
Metagenomics

This training will start with the presentation of a 16S pipeline (psbweb05.psb.ugent.be/lotus/) in a linux environment, using a minimal amount of linux commands. This will enable the preprocessing of the data going from raw reads to taxonomic tables and phylogenetic trees. The 2nd part of the...

Metagenomics http://tess.elixir-uk.org/materials/metagenomics This training will start with the presentation of a 16S pipeline (psbweb05.psb.ugent.be/lotus/) in a linux environment, using a minimal amount of linux commands. This will enable the preprocessing of the data going from raw reads to taxonomic tables and phylogenetic trees. The 2nd part of the training will give an overview of numerical ecology and takes part entierly in R. post-docs PhD students beginner bioinformaticians Life Science Researchers 2016-04-22 2016-08-31
RNA-Seq analysis for differential expression in GenePattern

We will investigate the following items: Quality control of the sequence reads to detect biases or contaminating adapters Mapping of the reads to the reference genome with use of a transcript database model Quality control of the mapping results Adjusting the mapping data to...

RNA-Seq analysis for differential expression in GenePattern http://tess.elixir-uk.org/materials/rna-seq-analysis-for-differential-expression-in-genepattern We will investigate the following items: Quality control of the sequence reads to detect biases or contaminating adapters Mapping of the reads to the reference genome with use of a transcript database model Quality control of the mapping results Adjusting the mapping data to compensate for artefacts like duplicates Calculate transcript counts usable for differential expression and merging of count tables Computing differential expression using EdgeR and DESeq2 The code pieces used during the training are made available through our Wiki as well as detailed results and can be copied and adapted for own user needs with minimal edits. Key results have been saved to our server and can be downloaded to fully reproduce the training. Life Science Researchers PhD students beginner bioinformaticians post-docs 2016-04-22 2017-10-09
Custom training: Ingenuity Pathway Analysis

The aim of this training is to teach you how to use Ingenuity Pathway Analysis (IPA) software on your own data. This can be for various applications: Creating and modifying biological networks e.g. which genes are involved in a certain disease Mapping data to biological processes,...

Scientific topics: Microarray experiment, Proteomics, Protein interactions, Metabolomics

Custom training: Ingenuity Pathway Analysis http://tess.elixir-uk.org/materials/custom-training-ingenuity-pathway-analysis The aim of this training is to teach you how to use Ingenuity Pathway Analysis (IPA) software on your own data. This can be for various applications: Creating and modifying biological networks e.g. which genes are involved in a certain disease Mapping data to biological processes, networks and pathways mapping a list of genes/proteins/chemicals mapping quantitative data e.g. microarray/proteomics/metabolomics data High quality visualisation of biological networks and pathways Assessing the biological significance of pathways in certain physiological conditions e.g. detecting overrepresented pathways in diseases Microarray experiment Proteomics Protein interactions Metabolomics Life Science Researchers post-docs PhD students 2016-04-22 2016-09-26
Custom training: OpenRefine

The aim of this training is to help you use OpenRefine on your own data. This can contain subjects like: load data files, import and parse data files from a URL clean data files: rename columns, transform and edit cells, split multivalue cells... transform data from one format to another:...

Scientific topics: Data quality management

Custom training: OpenRefine http://tess.elixir-uk.org/materials/custom-training-openrefine The aim of this training is to help you use OpenRefine on your own data. This can contain subjects like: load data files, import and parse data files from a URL clean data files: rename columns, transform and edit cells, split multivalue cells... transform data from one format to another: e.g. merge data from two files using  a column that is common to both data files, create new rows based on columns and vice versa... export cleaned, transformed data data manipulation pipelines data dashboards Data quality management Life Science Researchers PhD students post-docs 2016-04-22 2017-10-09
Introduction to gene regulation

This course presents a comprehensive overview of the principles and applications of studying eukaryotic gene regulation. The course combines lectures with hands-on exercises in which the participants learn to apply these principles to real data. The course will be based on freely available data...

Scientific topics: Molecular biology, Gene regulation, Gene expression

Introduction to gene regulation http://tess.elixir-uk.org/materials/introduction-to-gene-regulation This course presents a comprehensive overview of the principles and applications of studying eukaryotic gene regulation. The course combines lectures with hands-on exercises in which the participants learn to apply these principles to real data. The course will be based on freely available data and software. Molecular biology Gene regulation Gene expression Life Science Researchers PhD students post-docs 2016-04-22 2017-10-09
Initiation GIMP and Inkscape - Leuven

Introduction Bitmap vs vector images Image resolution PPI and DPI File formats VIB guidelines on image editing GIMP prepare images for publication Installation and documentation User Interface Import image files Image Properties Selection tools and options Transforming...

Initiation GIMP and Inkscape - Leuven http://tess.elixir-uk.org/materials/initiation-gimp-and-inkscape-leuven Introduction Bitmap vs vector images Image resolution PPI and DPI File formats VIB guidelines on image editing GIMP prepare images for publication Installation and documentation User Interface Import image files Image Properties Selection tools and options Transforming options Scaling and cropping Using Layers Contrast and brightness Undo/redo Image print size Saving/Exporting images Exercises Inkscape annotate plots and images, create figures (diagrams, schemes, ...), design posters Installation and documentation User interface Import image/vector files Drawing lines Creating paths Drawing objects Fill and stroke Aligning and distributing objects/nodes Z-order Adding text and text options Path effects Live path effects Diagrams Exporting images Exercises Life Science Researchers PhD students post-docs 2016-04-22 2016-06-15
Electronic Lab Notebook Introduction - Leuven

The Training consists of two parts: Introduction Access ways to your notebook, ELN installation instructions and house rules, where to find documentation and get support Hands-on-demo Creating notebooks/experiments, importing and exporting (MS Office) files, sharing data, using templates,...

Electronic Lab Notebook Introduction - Leuven http://tess.elixir-uk.org/materials/electronic-lab-notebook-introduction-leuven The Training consists of two parts: Introduction Access ways to your notebook, ELN installation instructions and house rules, where to find documentation and get support Hands-on-demo Creating notebooks/experiments, importing and exporting (MS Office) files, sharing data, using templates, advanced searching, printing, tips and tricks Life Science Researchers PhD students post-docs 2016-04-22 2016-06-15
Basic statistics theory

This training gives an introduction to the use of statistics for basic analyses of life sciences data. This training is a prerequisite introduction to a series of hands-on trainings on the statistical analysis of life sciences data: 'Basic statistics in R' and 'Basic statistics in Graphpad...

Basic statistics theory http://tess.elixir-uk.org/materials/basic-statistics-theory This training gives an introduction to the use of statistics for basic analyses of life sciences data. This training is a prerequisite introduction to a series of hands-on trainings on the statistical analysis of life sciences data: 'Basic statistics in R' and 'Basic statistics in Graphpad Prism'. If you want to follow one of these trainings, you have to follow this introduction. Ít will give you all the theoretical background that you need. Those that already have a strong statistical background may register directly for the 'Basic statistics in R, part II' training. Life Science Researchers PhD students post-docs 2016-04-22 2017-10-09
Analyzing flow cytometry data using FlowJo

Flowjo version10 is a newly designed version of the famous Flowjo software. In contrast with previous versions (iOS only), version 10 is now a multi-platform software tool (Windows, iOS, Linux). It now has a very intuitive user interface designed to analyze your data in a very practical and fast...

Analyzing flow cytometry data using FlowJo http://tess.elixir-uk.org/materials/analyzing-flow-cytometry-data-using-flowjo Flowjo version10 is a newly designed version of the famous Flowjo software. In contrast with previous versions (iOS only), version 10 is now a multi-platform software tool (Windows, iOS, Linux). It now has a very intuitive user interface designed to analyze your data in a very practical and fast way. The training will be focused on getting familiar with all the tools available within the software. Life Science Researchers PhD students post-docs 2016-04-22 2017-10-09
Basic bioinformatics concepts, databases and tools

During this 3-day introduction to bioinformatics, BITS will take you along a guided tour that covers all basic aspects of biological sequence analysis. This workshop is an ideal opportunity to get familiar with bioinformatics and its many faces! At the end, you should be able to start tackling...

Scientific topics: Sequence analysis

Basic bioinformatics concepts, databases and tools http://tess.elixir-uk.org/materials/basic-bioinformatics-concepts-databases-and-tools During this 3-day introduction to bioinformatics, BITS will take you along a guided tour that covers all basic aspects of biological sequence analysis. This workshop is an ideal opportunity to get familiar with bioinformatics and its many faces! At the end, you should be able to start tackling any basic bioinformatics problem: how to obtain relevant information about your gene, you know where to get the required sequence data, manipulate the sequences, and how basic software and algorithms function so you can fine-tune it in order the get the most out of your analysis. Sequence analysis Life Science Researchers PhD students post-docs 2016-04-22 2017-10-09
Introductory statistics in GraphPad Prism

This training gives an introduction to the use of statistics for basic analyses of life sciences data. The theoretical background obtained in the Basic statistics theory training  will be applied in a hands-on session on real-life data using the statistical software GraphPad...

Introductory statistics in GraphPad Prism http://tess.elixir-uk.org/materials/introductory-statistics-in-graphpad-prism This training gives an introduction to the use of statistics for basic analyses of life sciences data. The theoretical background obtained in the Basic statistics theory training  will be applied in a hands-on session on real-life data using the statistical software GraphPad Prism. BITS distributes the software for free to VIB scientists, for more information you can visit the GraphPad Prism page on the BITS web site. This is the reason why the training is limited to VIB scientists. Life Science Researchers PhD students post-docs 2016-04-22 2017-10-09