Target audience: postgrad or Scientists
This course focuses on genomic sequencing.
Topics covered:
- The changing landscape of genomics: From Sanger sequencing to Next Generation Sequencing
- Overview of Next Generation Sequencing platforms and their methodology
- Targeted resequencing
- Alignment, variant calling and...
Scientific topics: Rare diseases
Keywords: Rare Diseases & Research
Resource type: e-learning
This course focuses on molecular techniques. By the end, you will be able to demonstrate knowledge and applicability of the molecular principles behind:
- array comparative genomic hybridisation (array CGH);
- karyotyping;
- fluorescent in situ hybridisation (FISH);
- Southern blotting;
-...
Scientific topics: Rare diseases
Keywords: Rare Diseases & Research
Resource type: e-learning
3 online courses with academic credential to gain a deep insight into the potential of genomics in healthcare, and the clinical applications of molecular genetic techniques and next generation sequencing (NGS) technologies.
1. The Genomics Era: the Future of Genetics in Medicine
2. Genomic...
Scientific topics: Rare diseases
Keywords: Rare Diseases & Research
Resource type: e-learning
The WheatIS project aims at building an International Wheat Information System to support the wheat research community. The main objective is to provide a single-access web base system to access to the available data resources and bioinformatics tools. The project is...
Scientific topics: Data management
Keywords: wheat, information system, data discovery
Resource type: Webinar, Slides, Video
Do you want to identify and prioritise new therapeutic targets? Are you looking for associations of your gene of interest with a specific disease? Do you work in the area of drug repurposing? Are you interested in disease biology? If you said yes to any of these questions, this webinar is for...
Keywords: Europe PMC, Open Targets, gene-disease relationship, Text mining
Resource type: Webinar
In this workshop we focus on three aspects of FAIR data stewardship: Data sharing, publishing and archiving. Many scientists have an insufficient overview over data services, roles and their responsibilities towards safe data sharing, archiving and publishing. Shedding light on these roles helps...
Keywords: Data Life Cycle, FAIR, data management, data stewardship, data repositories, data sharing, data publication
Resource type: Slides, Training materials
This quick and simple tutorial demonstrates some of the easy plotting tools in the R core software.
the data are in the "data" directory and come from an old two-colour microarray experiment where spots on the array were printed with different buffers, in different concentrations and with...
Keywords: Bioinformatics, Microarray data analysis, Plotting data, R, Visualisation
Clinical Bioinformatics I is a 10 credit module of the new MSc in Clinical Bioinformatics, delivered by Nowgen/NGRL and the University of Manchester in the UK. Clinical Bioinformatics is one of the streams of the NHS Scientific Training Programme (STP). The programme is a mixture of work...
Keywords: Clinical bioinformatics, Genomics, Introduction bioinformatics
This presentation examines the available in silico tools for protein structure and function prediction. It examines the major protein family databases (PROSITE, PRINTS, Pfam, etc.), and explores why tools like PSI-BLAST, while convenient and easy to use, may not always give optimal results. The...
Keywords: Expert systems, Genequiz, Protein family characterisation, Protein family databases, Protein sequence analysis, Psi blast
This presentation introduces the background to the InterPro database: what it is, where it came from, and what was the vision behind its creation. It examines in particular whether the database has evolved in line with its original vision, and asks whether the resource is still fit for purpose.
Keywords: Integrated diagnostic tools, Protein family characterisation, Protein sequence analysis
A presentation designed to introduce the concept of protein family analysis and characterisation using motif-based methods, with a particular focus on protein fingerprinting. Following a general introduction to sequence analysis, and the fingerprint approach, specific examples are given to...
Keywords: Functional diagnosis, Protein family characterisation, Protein sequence analysis