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Keywords: Sequence analysis 

MGnify quick tour

This quick tour provides a brief introduction to MGnify - a free resource for analysis, visualisation and discovery of microbiome (metagenomic, metatranscriptomic, amplicon and assembly) datasets.

Scientific topics: Metagenomics

Keywords: Metagenomics, Sequence analysis, MGnify, Microbiology

Resource type: Tutorial

MGnify quick tour http://tess.elixir-uk.org/materials/mgnify-quick-tour This quick tour provides a brief introduction to MGnify - a free resource for analysis, visualisation and discovery of microbiome (metagenomic, metatranscriptomic, amplicon and assembly) datasets. Ola Tarkowska Lorna Richardson Metagenomics Metagenomics, Sequence analysis, MGnify, Microbiology Life Scientists
Bioinformatics - Food Detective: a Practical Guide

This Practical Guide introduces the idea of computers as tools to help understand aspects of biology. In particular, it looks at how DNA sequences can be used to identify specific organisms, why this is important in the food industry, and how this can be used to help de- tect food fraud. Analyses...

Scientific topics: Sequence analysis, DNA barcoding

Keywords: Basic bioinformatics, Bioinformatics schools, Dna barcoding, Food fraud, Sequence analysis, Sequence database searching, Species identification, Training material

Bioinformatics - Food Detective: a Practical Guide http://tess.elixir-uk.org/materials/bioinformatics-food-detective-a-practical-guide This Practical Guide introduces the idea of computers as tools to help understand aspects of biology. In particular, it looks at how DNA sequences can be used to identify specific organisms, why this is important in the food industry, and how this can be used to help de- tect food fraud. Analyses are run online using sequence data from the 4273pi project website: 4273pi.org. This Guide introduces a popular Web-based tool for searching biological sequence databases, and shows how to identify different spe- cies based on their specific DNA sequences – their ‘barcodes’. On reading the Guide and completing the exercises, you will be able to: i) explain what is meant by DNA barcoding; ii) search biological sequence databases using the online program BLAST; iii) judge the reliability of database-search results in terms of their statistical significance; and iv) evaluate the biological implications of search results with reference to food safety. Sequence analysis DNA barcoding Basic bioinformatics, Bioinformatics schools, Dna barcoding, Food fraud, Sequence analysis, Sequence database searching, Species identification, Training material 2020-06-23
Bioinformatics - the Power of Computers in Biology: A Practical Guide

This Practical Guide in the Bringing Bioinformatics into the Classroom series introduces simple bioinformatics approaches for database searching and sequence analysis. A ‘mystery’ gene is used as an exemplar: we first characterise the gene, then use it to explore the impact of gene loss in...

Scientific topics: Sequence analysis

Keywords: Basic bioinformatics, Basic linux commands, Bioinformatics schools, Gene loss, Genetic mutation, Raspberry pi computers, Sequence analysis, Sequence database searching, Training materials

Bioinformatics - the Power of Computers in Biology: A Practical Guide http://tess.elixir-uk.org/materials/bioinformatics-the-power-of-computers-in-biology-a-practical-guide This Practical Guide in the Bringing Bioinformatics into the Classroom series introduces simple bioinformatics approaches for database searching and sequence analysis. A ‘mystery’ gene is used as an exemplar: we first characterise the gene, then use it to explore the impact of gene loss in humans. Analyses are run both online and at the command line, the latter using Raspberry Pi computers running the 4273π variant of Linux (4273pi.org). Specifically, this Guide introduces a popular Web-based tool for searching biological sequence databases, and shows how similar functionality can be achieved using the Linux command line. On reading the Guide and completing the exercises, users will be able to: i) search biological sequence databases using the online program BLAST, and navigate GenPept sequence records; ii) execute some basic Linux commands to perform a set of simple file-manipulation tasks; iii) perform BLAST searches via the Linux command line; and iv) evaluate the biological implications of search results, with reference to mutations and function. Sequence analysis Basic bioinformatics, Basic linux commands, Bioinformatics schools, Gene loss, Genetic mutation, Raspberry pi computers, Sequence analysis, Sequence database searching, Training materials 2019-06-08
Exploring Microscope Platform

How to use the Microscope Platform to annotate and analyze microbial genomes.

Keywords: Annotation, Genomics, Metabolomics, Microbial evolution, Sequence analysis, Transcriptomics

Exploring Microscope Platform http://tess.elixir-uk.org/materials/exploring-microscope-platform How to use the Microscope Platform to annotate and analyze microbial genomes. Annotation, Genomics, Metabolomics, Microbial evolution, Sequence analysis, Transcriptomics
Understanding Multiple Sequence Alignments - Lecture Handouts & Utopia Hands-On

This presentation aims to provide a basic understanding of the range of contexts in which protein sequence alignments are used and are useful, focusing on the importance of sequence similarities and differences, and what they tell us. Overall, the objective is to offer different perspectives and...

Keywords: Multiple sequence alignment, Protein sequence analysis, Sequence analysis

Understanding Multiple Sequence Alignments - Lecture Handouts & Utopia Hands-On http://tess.elixir-uk.org/materials/understanding-multiple-sequence-alignments-lecture-handouts-utopia-hands-on This presentation aims to provide a basic understanding of the range of contexts in which protein sequence alignments are used and are useful, focusing on the importance of sequence similarities and differences, and what they tell us. Overall, the objective is to offer different perspectives and insights into the meaning of alignments, and to convey an understanding of the use of metaphor and its role in interpreting alignments. The talk is accompanied by a hands-on practical analysis using the Utopia sequence analysis suite. Multiple sequence alignment, Protein sequence analysis, Sequence analysis Biomedical researchers Life Science Researchers Postgraduate students 2013-12-17 2017-10-09
Introduction to Multiple Sequence Alignment

An introduction to multiple sequence alignments (MSAs) for bench biologists delivered as part of the EMBL Australia Masterclass on Protein Sequence Analysis http://oz-masterclass.wikispaces.com/ . Focuses on describing: the "anatomy" of a sequence alignment; two alternative interpretations of...

Keywords: Multiple sequence analysis, Protein structure, Sequence analysis

Introduction to Multiple Sequence Alignment http://tess.elixir-uk.org/materials/introduction-to-multiple-sequence-alignment An introduction to multiple sequence alignments (MSAs) for bench biologists delivered as part of the EMBL Australia Masterclass on Protein Sequence Analysis http://oz-masterclass.wikispaces.com/ . Focuses on describing: the "anatomy" of a sequence alignment; two alternative interpretations of alignmetns (structural and evolutionary), and ways of building manual and automatic alignments, and an introduction to JalView Multiple sequence analysis, Protein structure, Sequence analysis Bench biologists 2013-10-23 2017-10-09