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3 materials found

Contributors: Mikko Rautiainen  or David Castillo 


CPANG19 - Computational PANGenomics (2019)

Reference genomes have become central to bioinformatics approaches, and form the core of standard analyses using contemporary sequencing data. However, the use of linear reference genomes, which provide the sequence of one representative genome for a species, is increasingly becoming a limitation...

Keywords: Genomics

Resource type: Documentation, Exercise, Handout, Scripts

CPANG18 - Computational PANGenomics (2018)

Reference genomes have become central to bioinformatics approaches, and form the core of standard analyses using contemporary sequencing data. However, the use of linear reference genomes, which provide the sequence of one representative genome for a species, is increasingly becoming a limitation...

Keywords: Genomics

Resource type: Documentation, Exercise, Handout, Scripts

3DAROC18 - 3C-based data analysis and 3D reconstruction of chromatin folding (2018)

3C-based methods, such as Hi-C, produce a huge amount of raw data as pairs of DNA reads that are spatially close in the cell nucleus. Overall, these interaction matrices have been used to study how the genome folds within the nucleus, that is one of the most fascinating problems in modern...

Keywords: Hi-C

Resource type: Documentation, Exercise, Handout, Scripts