Sample size estimation - TeSS (Training eSupport System)

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Bioinformatics and Biomathematics Training Hub

The Bioinformatics and Biomathematics Training Hub (BBTH) is a BBSRC-funded collaborative project to coordinate the development and sharing of training materials and expertise across the UK’s National Institutes of Bioscience (NIB — http://www.nib.ac.uk/) for the increasingly important areas of bioinformatics and biomathematics.

Guided by our NIB partners, researcher surveys, and interactions with interested bodies such as Elixir-UK, we will work to ensure that best use is made of existing assets and capabilities, that best practice is shared across the NIB, and that redundant effort is minimised going forwards.

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Sample size estimation

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Power analysis is a method to estimate the samples sizes needed to detect statistical effects with high probability. This course provides an introduction to the basic principles of power analysis and goes through the variables for power calculation. It also addresses the issues associated with technical and biological replicates. The program is intended for people who have no prior knowledge of power. Basic statistical knowledge is extremely useful but prior attendance on a statistics course is not compulsary.

Course Content

Definition of Power
Variables in Power Analysis
Power anlaysis for
Comparing 2 proportions
Comparing 2 means
Comparing more than 2 means
Correlation

Course Material

Licence: Other (Non-Commercial)

Keywords: Power analysis, Sample size, Babraham Institute

Authors: Anne Segonds-Pichon