hands-on tutorial

Hands-on for 'Comparing inferred cell compositions using MuSiC deconvolution' tutorial

The questions this addresses are:
- How do the cell type distributions vary in bulk RNA samples across my variable of interest?
- For example, are beta cell proportions different in the pancreas data from diabetes and healthy patients?

The objectives are:
- Apply the MuSiC deconvolution to samples and compare the cell type distributions
- Compare the results from analysing different types of input, for example, whether combining disease and healthy references or not yields better results

Licence: Creative Commons Attribution 4.0 International

Keywords: single-cell, single-cell, mouse, human, deconvolution, bulk, transcriptomics

Target audience: Students

Resource type: hands-on tutorial

Authors: Mehmet Tekman, Wendi Bacon

Contributors: Mehmet Tekman, Wendi Bacon


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